Ceftiofur hydrochloride

2016-05-31 14:26:23   Click：

【Name】Ceftiofur hydrochloride
【CAS NO】103980-44-5
【characteristics】this product is a white to yellowish gray powder; Odourless, have led to wet. This product is soluble in water.
【pharmacological action】(1) the pharmacodynamics With a broad spectrum bactericidal action of gram-positive and gram-negative including producing beta lactamase strains are effective. Sensitive bacteria with Pasteur's bacteria, actinobacillus, haemophilus, samana, streptococcus, staphylococcus, etc. Antimicrobial activity than ammoniac benzyl west er, of streptococcus ketone strong antibacterial activity than the seconds.
Pharmacokinetic (2) the product of intramuscular and subcutaneous injection after absorb quickly, the high concentration of drug in blood and tissues, the effective blood drug concentration to maintain a long time, eliminate the slow, long half-life.
【Mainly used in the treatment of limited 】caused by sensitive bacteria of pigs, cattle, horses, dogs and a day-old chicks infectious diseases.
Bull: it is mainly used for hemolytic Pasteur's bacteria, kill Pasteur's bacteria and lethargy haemophilus respiratory disease caused by fever, pneumonia (transport). Is also effective to fester coryneform bacteria such as respiratory infections. Also can treat necrosis fusobacterium black foot rot caused by bacteroidetes.
Pig: used for pleuropneumonia actinobacillus, kill Pasteur salmonella bacteria, pigs cholera and streptococcus suis contribute to respiratory disease bacterial pneumonia (pigs).
Horse: main used in animal disease caused by streptococcus pneumoniae respiratory infections. The Pasteur bacterium, streptococcus and proteus, the Laplace bacteria such as respiratory infections and effective.
Dog: used for e. coli and singular deformation bacteria causing urinary tract infection. A day-old chicks: prevention and control of escherichia coli disease associated with chicks early mortality.
【 usage and dosage 】 an intramuscular injection quantity of 1-2 mg per kg of body weight of cattle horses 2-4 mg pigs for 3 to 5 mg 1 times a day even in 3 days.
Subcutaneous injection of a volume per kg of body weight dog a laparoscope, usually connected to a 2.2 g 1 times a day, 5-14
A day-old chicks every feather 0.08 0.2 mg (subcutaneously)
【 notes 】 (1) the horse under stress conditions the application of this product with acute diarrhea and can be deadly. In the event of withdrawal, immediately and adopt corresponding treatment measures.
(2) according to regulations of cephalosporins thiamethoxam injunctions sodium for injection dosage, treatment course and the drug delivery approach application, no stage to take medicine before slaughter waste no milk. Cefepime hydrochloride thiamethoxam take medicine of suspension injection duration: 2.
(3) mainly by the renal excretion of renal insufficiency animal should pay attention to adjust the dosage.
(4) for injection and physicochemical thiamethoxam cefuroxime sodium for injection before using the water dissolved, make 50 mg per mL contains cephalosporins thiamethoxam injunctions (2-8 ℃ refrigerating effect for 7 days, 15 to 30 ℃ mediator effect of 12 h) at room temperature.

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